Abstract Background Childhood-onset systemic lupus erythematosus (cSLE) is an incurable multi-systemic autoimmune disease.Interferon type I (IFN-I) plays a pivotal role in the pathogenesis of SLE.The objective of this study was to assess the prevalence of the IFN-I plush toy signature and the contribution of cytosolic nucleic acid receptors to IFN-
Global environmental changes can create novel habitats, promoting the growth of alien plants that often exhibit broad environmental tolerance and high phenotypic plasticity.However, the mechanisms underlying these growth promotory effects are unknown at present.Here, we conducted a phylogenetically controlled meta-analysis using data from 111 publi
Abstract Schizophrenia shows high heritability and several of the genes associated with this disorder are involved in calcium (Ca2+) signalling and synaptic function.One of these is the Rab-3 interacting molecule-1 (RIM1), which has recently Air Conditioner Pump been associated with schizophrenia by Genome Wide Association Studies (GWAS).However, i
In the context of international financial crisis, this paper aims to analyze the impact of the liquidity level on the monetary policy transmission effectiveness of the Moroccan Central Bank (Bank Al Maghrib, BAM).After a long period Air Conditioner Pump of liquidity excess, the Moroccan banking system through, since 2007, a liquidity shortage that
The precise number and pattern of axonal connections generated during brain development regulates animal behavior.Therefore, understanding how developmental signals interact to regulate axonal extension and retraction to achieve precise neuronal connectivity is a fundamental goal of neurobiology.We investigated this question in the developing adult